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The viral thymidine kinase gene as a tool for the study of mutagenesis in Trypanosoma brucei.

We have tested the use of thymidine kinase as a negative selection system for Trypanosoma brucei. To this end we have targeted a construct containing a Herpes simplex virus thymidine kinase (TK) gene into the ribosomal DNA array of procyclic T. brucei. This resulted in TK activity 30-50-fold above b...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Valdés, J, Taylor, M C, Cross, M A, Ligtenberg, M J, Rudenko, G, Borst, P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC145877/
https://ncbi.nlm.nih.gov/pubmed/8657559
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