The viral thymidine kinase gene as a tool for the study of mutagenesis in Trypanosoma brucei.
We have tested the use of thymidine kinase as a negative selection system for Trypanosoma brucei. To this end we have targeted a construct containing a Herpes simplex virus thymidine kinase (TK) gene into the ribosomal DNA array of procyclic T. brucei. This resulted in TK activity 30-50-fold above b...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145877/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.10.1809 |
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