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A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA
A central mystery in the function of site-specific DNA-binding proteins is the detailed mechanism for rapid location and binding of target sites in DNA. Human oxoguanine DNA glycosylase 1 (hOgg1), for example, must search out rare 8-oxoguanine lesions to prevent transversion mutations arising from o...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458645/ https://ncbi.nlm.nih.gov/pubmed/16585517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509723103 |
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