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Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair
An important feature of the common DNA oxidation product 8;oxo;7,8;dihydroguanine (OG) is its susceptibility to further oxidation to produce guanidinohydantion (Gh) and spiroiminodihydantoin (Sp) lesions. In the presence of amines, G or OG oxidation produces hydantoin amine adducts. Such adducts may...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906845/ https://ncbi.nlm.nih.gov/pubmed/23930966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4059469 |
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