Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair

An important feature of the common DNA oxidation product 8;oxo;7,8;dihydroguanine (OG) is its susceptibility to further oxidation to produce guanidinohydantion (Gh) and spiroiminodihydantoin (Sp) lesions. In the presence of amines, G or OG oxidation produces hydantoin amine adducts. Such adducts may...

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Detaylı Bibliyografya
Asıl Yazarlar: McKibbin, Paige L., Fleming, Aaron M., Towheed, Mohammad Atif, Van Houten, Bennett, Burrows, Cynthia J., David, Sheila S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906845/
https://ncbi.nlm.nih.gov/pubmed/23930966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4059469
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