Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme

Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development...

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Autors principals: Ratia, Kiira, Saikatendu, Kumar Singh, Santarsiero, Bernard D., Barretto, Naina, Baker, Susan C., Stevens, Raymond C., Mesecar, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458639/
https://ncbi.nlm.nih.gov/pubmed/16581910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510851103
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