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Dopamine D1/D5 receptor modulation of excitatory synaptic inputs to layer V prefrontal cortex neurons

Dopamine acts mainly through the D1/D5 receptor in the prefrontal cortex (PFC) to modulate neural activity and behaviors associated with working memory. To understand the mechanism of this effect, we examined the modulation of excitatory synaptic inputs onto layer V PFC pyramidal neurons by D1/D5 re...

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Auteurs principaux: Seamans, Jeremy K., Durstewitz, Daniel, Christie, Brian R., Stevens, Charles F., Sejnowski, Terrence J.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC14585/
https://ncbi.nlm.nih.gov/pubmed/11134516
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