Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors

To address the role of D1 receptors in the medial prefrontal cortex, we combined pharmacological and genetic manipulations to examine long-term synaptic potentiation (LTP)/long-term synaptic depression (LTD) in brain slices of rats and mice. We found that the D1 antagonist SCH23390 selectively block...

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Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Huang, Yan-You, Simpson, Eleanor, Kellendonk, Christoph, Kandel, Eric R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2004
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14981263/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308280101
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