Identification of an RNA-dependent ATPase activity in mammalian U5 snRNPs.

Nuclear pre-mRNA splicing requires ATP at several steps from spliceosome assembly to product release. Here, we demonstrate that an integral component of the 20S U5 snRNP is an RNA-dependent ATPase. The ATPase activity of 20S U5 and 25S [U4/U6.U5] snRNPs purified by glycerol gradient centrifugation i...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Laggerbauer, B, Lauber, J, Lührmann, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8600454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.5.868
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