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Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells

BACKGROUND: Thalidomide is an immunomodulatory agent, which arrests angiogenesis. The mechanism of anti-angiogenic activity of thalidomide is not fully understood. As nitric oxide is involved in angiogenesis, we speculate a cross-talk between thalidomide and nitric oxide signaling pathway to define...

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Detalhes bibliográficos
Main Authors: Tamilarasan, KP, Kolluru, Gopi Krishna, Rajaram, Megha, Indhumathy, M, Saranya, R, Chatterjee, Suvro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456963/
https://ncbi.nlm.nih.gov/pubmed/16584574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-7-17
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