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Transcriptional Compensation for Gene Loss Plays a Minor Role in Maintaining Genetic Robustness in Saccharomyces cerevisiae

If a gene is mutated and its function lost, are compensatory genes upregulated? We investigated whether genes are transcriptionally upregulated when their synthetic sick or lethal (SSL) partners are lost. We identified several new examples; however, remarkably few SSL pairs exhibited this phenomenon...

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Bibliografski detalji
Glavni autori: Wong, Sharyl L., Roth, Frederick P.
Format: Artigo
Jezik:Inglês
Izdano: Copyright © 2005 by the Genetics Society of America 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456790/
https://ncbi.nlm.nih.gov/pubmed/15998714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.046060
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