Transcriptional Compensation for Gene Loss Plays a Minor Role in Maintaining Genetic Robustness in Saccharomyces cerevisiae

If a gene is mutated and its function lost, are compensatory genes upregulated? We investigated whether genes are transcriptionally upregulated when their synthetic sick or lethal (SSL) partners are lost. We identified several new examples; however, remarkably few SSL pairs exhibited this phenomenon...

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Bibliographic Details
Main Authors: Wong, Sharyl L., Roth, Frederick P.
Format: Artigo
Language:Inglês
Published: Copyright © 2005 by the Genetics Society of America 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456790/
https://ncbi.nlm.nih.gov/pubmed/15998714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.046060
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