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Transcriptional Compensation for Gene Loss Plays a Minor Role in Maintaining Genetic Robustness in Saccharomyces cerevisiae
If a gene is mutated and its function lost, are compensatory genes upregulated? We investigated whether genes are transcriptionally upregulated when their synthetic sick or lethal (SSL) partners are lost. We identified several new examples; however, remarkably few SSL pairs exhibited this phenomenon...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
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Copyright © 2005 by the Genetics Society of America
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456790/ https://ncbi.nlm.nih.gov/pubmed/15998714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.046060 |
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