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dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae
We identified a viable allele (dut1-1) of the DUT1 gene that encodes the dUTPase activity in Saccharomyces cerevisiae. The Dut1-1 protein possesses a single amino acid substitution (Gly82Ser) in a conserved motif nearby the active site and exhibits a greatly reduced dUTPase activity. The dut1-1 sing...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440884/ https://ncbi.nlm.nih.gov/pubmed/16617146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl139 |
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