Llwytho...

Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae

High transcription is associated with genetic instability, notably increased spontaneous mutation rates, which is a phenomenon termed Transcription-Associated-Mutagenesis (TAM). In this study, we investigated TAM using the chromosomal CAN1 gene under the transcriptional control of two strong and ind...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Takahashi, Diane T., Burguiere-Slezak, Guenaelle, Van der Kemp, Patricia Auffret, Boiteux, Serge
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021075/
https://ncbi.nlm.nih.gov/pubmed/21177431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012582108
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