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Signal transduction through mu kappa B-cell receptors expressed on pre-B cells is different from that through B-cell receptors on mature B cells.

We introduced kappa light chain genes into pre-B cells to increase the surface mu HC expression, and established transfectants expressing mature type of B-cell receptors (BCR) on pre-B-cell surfaces. Since the cytoplasmic conformations of the reconstituted BCR and intrinsic pre-B-cell receptor (pre-...

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Detalhes bibliográficos
Main Authors: Nakamura, T, Koyama, M, Yoneyama, A, Higashihara, M, Kawakami, T, Yamamura, H, Sada, K, Okumura, K, Kurokawa, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456641/
https://ncbi.nlm.nih.gov/pubmed/8881762
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