Reversal of mucosal tolerance by subcutaneous administration of interleukin-12 at the site of attempted sensitization.

Oral feeding of proteins causes peripheral T-cell tolerance, as revealed by reduced delayed-type hypersensitivity (DTH) reactivity after immunization. This type of tolerance can be due both to passive T-cell anergy and active immunosuppression. Using ovalbumin-fed mice we studied whether putatively...

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Detalhes bibliográficos
Main Authors: Claessen, A M, von Blomberg, B M, De Groot, J, Wolvers, D A, Kraal, G, Scheper, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456349/
https://ncbi.nlm.nih.gov/pubmed/8774351
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