Mucosal Administration of Collagen V Ameliorates the Atherosclerotic Plaque Burden by Inducing Interleukin 35-dependent Tolerance

We have shown previously that collagen V (col(V)) autoimmunity is a consistent feature of atherosclerosis in human coronary artery disease and in the Apoe(−/−) mouse model. We have also shown sensitization of Apoe(−/−) mice with col(V) to markedly increase the atherosclerotic burden, providing evide...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Park, Arick C., Huang, Guorui, Jankowska-Gan, Ewa, Massoudi, Dawiyat, Kernien, John F., Vignali, Dario A., Sullivan, Jeremy A., Wilkes, David S., Burlingham, William J., Greenspan, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751380/
https://ncbi.nlm.nih.gov/pubmed/26721885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681882
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