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Human Prostate Tumor Antigen-Specific CD8+ Regulatory T Cells are Inhibited by CTLA-4 or IL-35 Blockade
Regulatory T cells play important roles in cancer development and progression by limiting the generation of innate and adaptive anti-tumor immunity. We hypothesized that in addition to natural CD4+CD25+ Tregs and myeloid-derived suppressor cells, tumor antigen-specific regulatory T cells interfere w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735346/ https://ncbi.nlm.nih.gov/pubmed/23152566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201744 |
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