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Interleukin 12 at the site of disease in tuberculosis.

Interleukin 12 (IL-12), a heterodimeric cytokine composed of p40 and p35 chains, has potent immunologic effects in vitro. We used tuberculous pleuritis as a model to study the immunoregulatory potential of IL-12 in vivo at the site of human infectious disease. Messenger RNAs for p40 and p35 were det...

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Detalhes bibliográficos
Main Authors: Zhang, M, Gately, M K, Wang, E, Gong, J, Wolf, S F, Lu, S, Modlin, R L, Barnes, P F
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC294229/
https://ncbi.nlm.nih.gov/pubmed/7909320
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