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Novel method for high throughput DNA methylation marker evaluation using PNA-probe library hybridization and MALDI-TOF detection

The methylation of CpG dinucleotides has become a topic of great interest in cancer research, and the methylation of promoter regions of several tumor suppressor genes has been identified as a marker of tumorigenesis. Evaluation of DNA methylation markers in tumor tissue requires hundreds of samples...

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Autores principales: Schatz, Philipp, Distler, Jürgen, Berlin, Kurt, Schuster, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456329/
https://ncbi.nlm.nih.gov/pubmed/16670426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl218
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