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Peptide nucleic acid probes with charged photocleavable mass markers: Towards PNA-based MALDI-TOF MS genetic analysis

Halogen-labelled peptide organic acid (HPOA) monomers have been synthesised and incorporated into sequence-specific peptide nucleic acid (PNA) probes. Three different types of probe have been prepared; the unmodified PNA probe, the PNA probe with a mass marker, and the PNA probe with photocleavable...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ball, Rachel J, Green, Philip S, Gale, Nittaya, Langley, G John, Brown, Tom
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109446/
https://ncbi.nlm.nih.gov/pubmed/21687524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.1.1.12199
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