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Analysis of Repeat-Mediated Deletions in the Mitochondrial Genome of Saccharomyces cerevisiae
Mitochondrial DNA deletions and point mutations accumulate in an age-dependent manner in mammals. The mitochondrial genome in aging humans often displays a 4977-bp deletion flanked by short direct repeats. Additionally, direct repeats flank two-thirds of the reported mitochondrial DNA deletions. The...
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| Format: | Artigo |
| Sprache: | Inglês |
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Copyright © 2005 by the Genetics Society of America
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456083/ https://ncbi.nlm.nih.gov/pubmed/16157666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.047092 |
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