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Analysis of Repeat-Mediated Deletions in the Mitochondrial Genome of Saccharomyces cerevisiae

Mitochondrial DNA deletions and point mutations accumulate in an age-dependent manner in mammals. The mitochondrial genome in aging humans often displays a 4977-bp deletion flanked by short direct repeats. Additionally, direct repeats flank two-thirds of the reported mitochondrial DNA deletions. The...

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Autori principali: Phadnis, Naina, Sia, Rey A., Sia, Elaine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright © 2005 by the Genetics Society of America 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456083/
https://ncbi.nlm.nih.gov/pubmed/16157666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.047092
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