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Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction
The VS nucleolytic ribozyme has a core comprising five helices organized by two three-way junctions. The ribozyme can act in trans on a hairpin-loop substrate, with which it interacts via tertiary contacts. We have determined that one of the junctions (2-3-6) undergoes two-stage ion-dependent foldin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145516/ https://ncbi.nlm.nih.gov/pubmed/11250907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.6.1415 |
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