Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchor

The human cytomegalovirus (HCMV) US11 polypeptide is a type I membrane glycoprotein that targets major histocompatibility complex (MHC) class I molecules for destruction in a proteasome-dependent manner. Although the US11 signal sequence appears to be a classical N-terminal signal peptide in terms o...

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Publicado en:	EMBO J
Autores principales:	Rehm, Armin, Stern, Patrick, Ploegh, Hidde L., Tortorella, Domenico
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 2001
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.7.1573
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