The Human Cytomegalovirus US10 Gene Product Delays Trafficking of Major Histocompatibility Complex Class I Molecules

Human cytomegalovirus (HCMV) US10 encodes a glycoprotein that binds to major histocompatibility complex (MHC) class I heavy chains. While expression of US10 delays the normal trafficking of MHC class I molecules out of the endoplasmic reticulum, US10 does not obviously facilitate or inhibit the acti...

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Detalhes bibliográficos
Main Authors: Furman, Margo H., Dey, Neelendu, Tortorella, Domenico, Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136774/
https://ncbi.nlm.nih.gov/pubmed/12388737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11753-11756.2002
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