Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

Protein folding mediated by the Hsp70 family of molecular chaperones requires both ATP and the co-chaperone Hdj-1. BAG-1 was recently identified as a bcl-2-interacting, anti-apoptotic protein that binds to the ATPase domain of Hsp70 and prevents the release of the substrate. While this suggested tha...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Thress, Kenneth, Song, Jaewhan, Morimoto, Richard I., Kornbluth, Sally
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2001
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11230127/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.5.1033
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!