Structural polymorphism of the major capsid protein of rotavirus

Rotaviruses are important human pathogens with a triple-layered icosahedral capsid. The major capsid protein VP6 is shown here to self-assemble into spherical or helical particles mainly depending upon pH. Assembly is inhibited either by low pH (<3.0) or by a high concentration (>100 mM) of di...

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Bibliografiske detaljer
Main Authors: Lepault, Jean, Petitpas, Isabelle, Erk, Inge, Navaza, Jorge, Bigot, Dominique, Dona, Michel, Vachette, Patrice, Cohen, Jean, Rey, Félix A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC145494/
https://ncbi.nlm.nih.gov/pubmed/11285214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1498
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