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Antibodies to Rotavirus Outer Capsid Glycoprotein VP7 Neutralize Infectivity by Inhibiting Virion Decapsidation

The rotavirus capsid is composed of three concentric protein layers. Proteins VP4 and VP7 comprise the outer layer. VP4 forms spikes, is the viral attachment protein, and is cleaved by trypsin into VP8* and VP5*. VP7 is a glycoprotein and the major constituent of the outer protein layer. Both VP4 an...

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Hlavní autoři: Ludert, Juan Ernesto, Ruiz, Marie Christine, Hidalgo, Carlos, Liprandi, Ferdinando
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136269/
https://ncbi.nlm.nih.gov/pubmed/12050377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.13.6643-6651.2002
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