Antibodies to Rotavirus Outer Capsid Glycoprotein VP7 Neutralize Infectivity by Inhibiting Virion Decapsidation

The rotavirus capsid is composed of three concentric protein layers. Proteins VP4 and VP7 comprise the outer layer. VP4 forms spikes, is the viral attachment protein, and is cleaved by trypsin into VP8* and VP5*. VP7 is a glycoprotein and the major constituent of the outer protein layer. Both VP4 an...

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Bibliografiska uppgifter
Huvudupphovsmän: Ludert, Juan Ernesto, Ruiz, Marie Christine, Hidalgo, Carlos, Liprandi, Ferdinando
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC136269/
https://ncbi.nlm.nih.gov/pubmed/12050377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.13.6643-6651.2002
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