Antibodies to Rotavirus Outer Capsid Glycoprotein VP7 Neutralize Infectivity by Inhibiting Virion Decapsidation

The rotavirus capsid is composed of three concentric protein layers. Proteins VP4 and VP7 comprise the outer layer. VP4 forms spikes, is the viral attachment protein, and is cleaved by trypsin into VP8* and VP5*. VP7 is a glycoprotein and the major constituent of the outer protein layer. Both VP4 an...

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Pubblicato in:	J Virol
Autori principali:	Ludert, Juan Ernesto, Ruiz, Marie Christine, Hidalgo, Carlos, Liprandi, Ferdinando
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12050377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.13.6643-6651.2002
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