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Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone

The evolutionarily conserved DnaJ proteins are essential components of Hsp70 chaperone systems. The DnaJ homologue of Escherichia coli associates with chaperone substrates and mediates their ATP hydrolysis-dependent locking into the binding cavity of its Hsp70 partner, DnaK. To determine the substra...

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Bibliografiske detaljer
Main Authors: Rüdiger, Stefan, Schneider-Mergener, Jens, Bukau, Bernd
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC145471/
https://ncbi.nlm.nih.gov/pubmed/11230128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.5.1042
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