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Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries.

Hsp70 chaperones assist protein folding by ATP-dependent association with linear peptide segments of a large variety of folding intermediates. The molecular basis for this ability to differentiate between native and non-native conformers was investigated for the DnaK homolog of Escherichia coli. We...

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Main Authors: Rüdiger, S, Germeroth, L, Schneider-Mergener, J, Bukau, B
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169754/
https://ncbi.nlm.nih.gov/pubmed/9130695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.7.1501
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