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A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements
While decapping plays a major role in mRNA turnover in yeast, biochemical evidence for a similar activity in mammalian cells has been elusive. We have now identified a decapping activity in HeLa cytoplasmic extracts that releases (7me)GDP from capped transcripts. Decapping is activated in extracts b...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145468/ https://ncbi.nlm.nih.gov/pubmed/11230136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.5.1134 |
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