A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements
While decapping plays a major role in mRNA turnover in yeast, biochemical evidence for a similar activity in mammalian cells has been elusive. We have now identified a decapping activity in HeLa cytoplasmic extracts that releases (7me)GDP from capped transcripts. Decapping is activated in extracts b...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11230136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.5.1134 |
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