Induction of immunoglobulin-secreting cells by 2-mercaptoethanol in in vitro culture of B cells from autoimmune mice.

Splenic B cells from older MRL/Mp-lpr/lpr (MRL/1) and male BXSB mice responded to 2-mercaptoethanol (2-ME) in in vitro culture and generated immunoglobulin-secreting cells (IgSC). Optimal concentration of 2-ME to induce IgSC was 5 X 10(-5) M. Kinetic studies revealed that the generation of IgSC was...

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Hlavní autoři: Fujiwara, M, Kariyone, A I
Médium: Artigo
Jazyk:Inglês
Vydáno: 1984
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1454562/
https://ncbi.nlm.nih.gov/pubmed/6231244
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