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Activation of murine B lymphocytes by anti-immunoglobulin is an inductive signal leading to immunoglobulin secretion

Cultures of isolated mouse splenic B lymphocytes activated by the divalent F(ab')2 fragment of purified rabbit anti-mouse Fab or class- specific anti-mouse IgM antibodies can be driven on to high rate Ig secretion by the addition of the supernatant fluid of a 24-h culture of concanavalin A-acti...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1980
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185896/
https://ncbi.nlm.nih.gov/pubmed/6967509
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