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Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice

Experimental autoimmune encephalomyelitis (EAE) is an animal model for autoimmune central nervous system disease mediated by CD4 T cells. To examine the role of B cells in the induction of EAE, we used B10.PL (I-A(u)) mice rendered deficient in B cells by deletion of their μ chain transmembrane regi...

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Detalles Bibliográficos
Main Authors: Wolf, Susan D., Dittel, Bonnie N., Hardardottir, Fridrika, Janeway, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196394/
https://ncbi.nlm.nih.gov/pubmed/8976182
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