Mechanism of Tet(O)-mediated tetracycline resistance

Tet(O) is an elongation factor-like protein which confers resistance to the protein synthesis inhibitor tetracycline by promoting the release of the drug from its inhibitory site on the ribosome. Here we investigated the interaction of Tet(O) with the elongating ribosome and show, using dimethyl sul...

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Publié dans:	EMBO J
Auteurs principaux:	Connell, Sean R., Trieber, Catharine A., Dinos, George P., Einfeldt, Edda, Taylor, Diane E., Nierhaus, Knud H.
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2003
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg093
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