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Mechanism of Tet(O)-mediated tetracycline resistance

Tet(O) is an elongation factor-like protein which confers resistance to the protein synthesis inhibitor tetracycline by promoting the release of the drug from its inhibitory site on the ribosome. Here we investigated the interaction of Tet(O) with the elongating ribosome and show, using dimethyl sul...

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Detalhes bibliográficos
Main Authors: Connell, Sean R., Trieber, Catharine A., Dinos, George P., Einfeldt, Edda, Taylor, Diane E., Nierhaus, Knud H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145453/
https://ncbi.nlm.nih.gov/pubmed/12574130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg093
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