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Mechanism of Tet(O)-mediated tetracycline resistance

Tet(O) is an elongation factor-like protein which confers resistance to the protein synthesis inhibitor tetracycline by promoting the release of the drug from its inhibitory site on the ribosome. Here we investigated the interaction of Tet(O) with the elongating ribosome and show, using dimethyl sul...

詳細記述

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書誌詳細
出版年:EMBO J
主要な著者: Connell, Sean R., Trieber, Catharine A., Dinos, George P., Einfeldt, Edda, Taylor, Diane E., Nierhaus, Knud H.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145453/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574130/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg093
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