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Dimerization with PEBP2β protects RUNX1/AML1 from ubiquitin–proteasome-mediated degradation

The RUNX family genes are the mammalian homologs of the Drosophila genes runt and lozenge, and members of this family function as master regulators of definitive hematopoiesis and osteogenesis. The RUNX genes encode the α subunit of the transcription factor PEBP2/CBF. The β subunit consists of the n...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Huang, Gang, Shigesada, Katsuya, Ito, Kosei, Wee, Hee-Jun, Yokomizo, Tomomasa, Ito, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2001
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145428/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179217/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.4.723
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