Dimerization with PEBP2β protects RUNX1/AML1 from ubiquitin–proteasome-mediated degradation

The RUNX family genes are the mammalian homologs of the Drosophila genes runt and lozenge, and members of this family function as master regulators of definitive hematopoiesis and osteogenesis. The RUNX genes encode the α subunit of the transcription factor PEBP2/CBF. The β subunit consists of the n...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Huang, Gang, Shigesada, Katsuya, Ito, Kosei, Wee, Hee-Jun, Yokomizo, Tomomasa, Ito, Yoshiaki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179217/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.4.723
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