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Protective Levels of Diphtheria-Neutralizing Antibody Induced in Healthy Volunteers by Unilateral Priming-Boosting Intranasal Immunization Associated with Restricted Ipsilateral Mucosal Secretory Immunoglobulin A

Subunit intranasal vaccines offer the prospect of inducing combined systemic-mucosal immunity against mucosally transmitted infections such as human immunodeficiency virus. However, although human studies have demonstrated the induction of active immunity, secretory immunoglobulin A (sIgA) responses...

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Guardat en:
Publicat a:Infect Immun
Autors principals: Mills, Kingston H. G., Cosgrove, Catherine, McNeela, Edel A., Sexton, Amy, Giemza, Rafaela, Jabbal-Gill, Inderjit, Church, Anne, Lin, Wu, Illum, Lisbeth, Podda, Audino, Rappuoli, Rino, Pizza, Mariagrazia, Griffin, George E., Lewis, David J. M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2003
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12540551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.2.726-732.2003
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