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Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine.

Whooping cough caused by Bordetella pertussis is a re-emerging infectious disease despite the introduction of safer acellular pertussis vaccines (Pa). One explanation for this is that Pa are less protective than the more reactogenic whole cell pertussis vaccines (Pw) that they replaced. Although Pa...

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Váldodahkkit: Pádraig J Ross, Caroline E Sutton, Sarah Higgins, Aideen C Allen, Kevin Walsh, Alicja Misiak, Ed C Lavelle, Rachel M McLoughlin, Kingston H G Mills
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2013-01-01
Ráidu:PLoS Pathogens
Liŋkkat:http://europepmc.org/articles/PMC3617212?pdf=render
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