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Destructive Arthritis in Vaccinated Interferon Gamma-Deficient Mice Challenged with Borrelia burgdorferi: Modulation by Tumor Necrosis Factor Alpha

We found that Borrelia burgdorferi-vaccinated gamma interferon-deficient (IFN-γ(0)) mice challenged with B. burgdorferi developed prominent chronic destructive osteoarthropathy. When these mice were treated with anti-tumor necrosis factor alpha (TNF-α) antibody, the severity of the destructive osteo...

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Vydáno v:Clin Diagn Lab Immunol
Hlavní autoři: Christopherson, John A., Munson, Erik L., England, Douglas M., Croke, Cindy L., Remington, Monica C., Molitor, Melanie L., DeCoster, David J., Callister, Steven M., Schell, Ronald F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12522038/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.10.1.44-52.2003
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