Destructive Arthritis in Vaccinated Interferon Gamma-Deficient Mice Challenged with Borrelia burgdorferi: Modulation by Tumor Necrosis Factor Alpha

We found that Borrelia burgdorferi-vaccinated gamma interferon-deficient (IFN-γ(0)) mice challenged with B. burgdorferi developed prominent chronic destructive osteoarthropathy. When these mice were treated with anti-tumor necrosis factor alpha (TNF-α) antibody, the severity of the destructive osteo...

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Detalhes bibliográficos
Main Authors: Christopherson, John A., Munson, Erik L., England, Douglas M., Croke, Cindy L., Remington, Monica C., Molitor, Melanie L., DeCoster, David J., Callister, Steven M., Schell, Ronald F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Microbial Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145283/
https://ncbi.nlm.nih.gov/pubmed/12522038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.10.1.44-52.2003
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