Destructive Arthritis in Vaccinated Interferon Gamma-Deficient Mice Challenged with Borrelia burgdorferi: Modulation by Tumor Necrosis Factor Alpha

We found that Borrelia burgdorferi-vaccinated gamma interferon-deficient (IFN-γ(0)) mice challenged with B. burgdorferi developed prominent chronic destructive osteoarthropathy. When these mice were treated with anti-tumor necrosis factor alpha (TNF-α) antibody, the severity of the destructive osteo...

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Bibliografiske detaljer

Udgivet i:	Clin Diagn Lab Immunol
Principais autores:	Christopherson, John A., Munson, Erik L., England, Douglas M., Croke, Cindy L., Remington, Monica C., Molitor, Melanie L., DeCoster, David J., Callister, Steven M., Schell, Ronald F.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Microbial Immunology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145283/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12522038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.10.1.44-52.2003
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