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Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1
The ubiquitin C-terminal hydrolase UCH-L1 (PGP9.5) comprises >1% of total brain protein but is almost absent from other tissues [Wilkinson, K. D., et al. (1989) Science 246, 670–673]. Mutations in the UCH-L1 gene have been reported to be linked to susceptibility to and protection from Parkinson&#...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450230/ https://ncbi.nlm.nih.gov/pubmed/16537382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510403103 |
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