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Reverse genetics system for introduction of site-specific mutations into the double-stranded RNA genome of infectious rotavirus

We describe here the successful establishment of a reverse genetics system for rotavirus (RV), a member of the Reoviridae family whose genome consists of 10–12 segmented dsRNA. The system is based on the recombinant vaccinia virus T7 RNA polymerase-driven procedure for supplying artificial viral mRN...

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מידע ביבליוגרפי
Main Authors: Komoto, Satoshi, Sasaki, Jun, Taniguchi, Koki
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450225/
https://ncbi.nlm.nih.gov/pubmed/16537420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509385103
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