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Reverse genetics system for introduction of site-specific mutations into the double-stranded RNA genome of infectious rotavirus
We describe here the successful establishment of a reverse genetics system for rotavirus (RV), a member of the Reoviridae family whose genome consists of 10–12 segmented dsRNA. The system is based on the recombinant vaccinia virus T7 RNA polymerase-driven procedure for supplying artificial viral mRN...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450225/ https://ncbi.nlm.nih.gov/pubmed/16537420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509385103 |
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