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Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

Obstruction of bile flow results in bacterial proliferation and mucosal injury in the small intestine that can lead to the translocation of bacteria across the epithelial barrier and systemic infection. These adverse effects of biliary obstruction can be inhibited by administration of bile acids. He...

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Hlavní autoři: Inagaki, Takeshi, Moschetta, Antonio, Lee, Youn-Kyoung, Peng, Li, Zhao, Guixiang, Downes, Michael, Yu, Ruth T., Shelton, John M., Richardson, James A., Repa, Joyce J., Mangelsdorf, David J., Kliewer, Steven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450165/
https://ncbi.nlm.nih.gov/pubmed/16473946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509592103
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