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Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

Obstruction of bile flow results in bacterial proliferation and mucosal injury in the small intestine that can lead to the translocation of bacteria across the epithelial barrier and systemic infection. These adverse effects of biliary obstruction can be inhibited by administration of bile acids. He...

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Bibliographic Details
Main Authors: Inagaki, Takeshi, Moschetta, Antonio, Lee, Youn-Kyoung, Peng, Li, Zhao, Guixiang, Downes, Michael, Yu, Ruth T., Shelton, John M., Richardson, James A., Repa, Joyce J., Mangelsdorf, David J., Kliewer, Steven A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450165/
https://ncbi.nlm.nih.gov/pubmed/16473946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509592103
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