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Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment

Human metastatic melanoma cells express a dedifferentiated, plastic phenotype, which may serve as a selective advantage, because melanoma cells invade various microenvironments. Over the last three decades, there has been an increased focus on the role of the tumor microenvironment in cancer progres...

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Autors principals: Kulesa, Paul M., Kasemeier-Kulesa, Jennifer C., Teddy, Jessica M., Margaryan, Naira V., Seftor, Elisabeth A., Seftor, Richard E. B., Hendrix, Mary J. C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450149/
https://ncbi.nlm.nih.gov/pubmed/16505384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506977103
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